Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9926779 | 0.94 | MAPT (0.52) | MAPTMEN1KMT2AGFERTDP1 | |
| SCHEMBL23357515 | 0.91 | MAPT (0.49) | MAPTMEN1KMT2AGFERTDP1 | |
| SCHEMBL30904747 | 0.91 | MAPT (0.49) | MAPTMEN1KMT2AGFERTDP1 | |
| SCHEMBL29203292 | 0.87 | MAPT (0.51) | MAPTMEN1KMT2AGFERTDP1 | |
| SCHEMBL30662661 | 0.83 | KMT2A (0.51) | MAPTMEN1KMT2AGFERTDP1 | |
| SCHEMBL27267582 | 0.82 | PTGER4 (0.56) | MAPTMEN1KMT2AGAAPTGER4 | |
| SCHEMBL14471226 | 0.79 | KAT2B (0.57) | MAPTMEN1KMT2ATDP1GAA | |
| SCHEMBL4978573 | 0.78 | MAPT (0.56) | MAPTMEN1KMT2AGFERTDP1 | |
| SCHEMBL6644250 | 0.77 | PRKCQ (0.46) | CYP3A4 | |
| SCHEMBL6814431 | 0.77 | PTGER4 (0.50) | MAPTMEN1KMT2AGAAPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776522-B | Substituted heteroaryl compounds, compositions and uses thereof | 广东东阳光药业有限公司 | 2020-12-29 | — | — | CN | disclosed |