⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39636 | 0.79 | — | — | |
| SCHEMBL15870902 | 0.78 | — | — | |
| SCHEMBL7704419 | 0.78 | — | — | |
| Water SCHEMBL1275976 | 0.77 | — | — | |
| SCHEMBL3100807 | 0.74 | — | — | |
| SCHEMBL87629 | 0.74 | — | — | |
| SCHEMBL289070 | 0.74 | — | — | |
| SCHEMBL9113300 | 0.70 | — | — | |
| SCHEMBL2790521 | 0.70 | — | — | |
| SCHEMBL20595744 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732552-A | Method for synthesizing 1, 3-oxazole-2-thioketone by palladium catalysis | 西北大学 | 2020-10-02 | — | — | CN | claimed |
| CN-106496153-B | A kind of 1,3-oxazoles -2- thiones neuraminidase inhibitors and preparation method thereof | 上海应用技术大学 | 2018-07-10 | — | — | CN | claimed |
| CN-111732552-A | Method for synthesizing 1, 3-oxazole-2-thioketone by palladium catalysis | 西北大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-111732552-A | Method for synthesizing 1, 3-oxazole-2-thioketone by palladium catalysis | 西北大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-111732552-A | Method for synthesizing 1, 3-oxazole-2-thioketone by palladium catalysis | 西北大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-107011282-B | N- [4- (alkoxy)-benzenesulfonyl] -5- aryl-oxazole -2- thiones neuraminidase inhibitor | 上海应用技术大学 | 2019-10-01 | — | — | CN | disclosed |
| CN-106496153-B | A kind of 1,3-oxazoles -2- thiones neuraminidase inhibitors and preparation method thereof | 上海应用技术大学 | 2018-07-10 | — | — | CN | disclosed |
| CN-107011282-A | The thiones neuraminidase inhibitor of N [4 (alkoxy) benzenesulfonyl] 5 aryl oxazole 2 | 上海应用技术大学 | 2017-08-04 | — | — | CN | disclosed |
| CN-106496153-A | 2 thiones neuraminidase inhibitor of a kind of 1,3 oxazole and preparation method thereof | 上海应用技术大学 | 2017-03-15 | — | — | CN | disclosed |
| CN-101973915-B | Intermediate of synthetic imipenem medicine as well as preparation method and application thereof | SHANGHAI BUDDY BIO PHARM INTERMEDIATES LTD | 2013-06-26 | — | — | CN | disclosed |
| CN-102388026-A | Dichloropropene compound and application thereof | SINOCHEM CORP | 2012-03-21 | — | — | CN | disclosed |
| EP-1809653-A1 | SUBSTITUTED NONADEPSIPEPTIDES | AiCuris GmbH & Co. KG (DE) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006042654-A1 | SUBSTITUTED NONADEPSIPEPTIDES | AICURIS GMBH & CO. KG (DE) | 2006-04-27 | — | — | WO | disclosed |
| EP-1207161-B1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2006-01-18 | — | — | EP | disclosed |
| CN-1668609-A | Substituted 4-aryl-4H-pyrrolo[2,3-H]chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA INC (US) | 2005-09-14 | — | — | CN | disclosed |
| US-6777410-B2 | SUCH AS 9-(2-METHOXYPHENYL)-3-(1-METHYLETHYL)-(1,3)OXAZOLO-(2,3)ISOINDOLE-2,5(3H,9H)-DIONE; DIABETES AND COMPLICATIONS; OBESITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20040053923-A1 | Novel isoindole derivatives | BANYU PHARMACEUTICAL CO., LTD. | 2004-03-18 | — | — | US | disclosed |
| US-6608098-B1 | Diabetes or obesity, 2-(4-(3-isopropyl-2,5-dioxo-2,3-dihydro-1H-pyrrolo(2,1-a) isoindol-9(5H)-yl)phenoxy)-N-propylacetamide | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1207161-A1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |
| CN-1143958-A | (4,4-difluorobut-3-enylthio-)-substituted heterocyclic or carbocyclic ring compounds | ZENECA LTD (GB) | 1997-02-26 | — | — | CN | disclosed |