SCHEMBL28514869

SCHEMBL28514869

COCCOc1cc(OC(N)=O)ccc1C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
HTT P42858 2/20 0.43
KMT2A Q03164 2/20 0.43
MRGPRX4 Q96LA9 1/20 0.42
KIF11 P52732 1/20 0.41
BRAF P15056 4/20 0.41
RAF1 P04049 2/20 0.41
HPGD P15428 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
MEN1 O00255 1/20 0.38
AR P10275 2/20 0.38
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37
RXFP1 Q9HBX9 1/20 0.36
NOTUM Q6P988 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28102672 0.80 HTT (0.43) KDM4EHTTKMT2AMRGPRX4KIF11
SCHEMBL4644874 0.80 HTT (0.39) KDM4EHTTKMT2AMRGPRX4ALDH1A1
SCHEMBL24214079 0.77 HTT (0.51) KDM4EHTTKMT2AMRGPRX4HPGD
SCHEMBL13680229 0.76 AR (0.43) KDM4EHTTKMT2AKIF11BRAF
SCHEMBL4644879 0.76 KDM4E (0.40) KDM4EHTTKMT2AMRGPRX4ALDH1A1
SCHEMBL24214083 0.76 NOTUM (0.57) KDM4EHTTKMT2AMRGPRX4BRAF
SCHEMBL4640469 0.75 ELANE (0.44) KDM4EHTTKMT2AMRGPRX4ALDH1A1
Hydrochloric Acid SCHEMBL17393004 0.75 AR (0.42) KDM4EHTTKMT2AKIF11BRAF
SCHEMBL28102671 0.74 HTT (0.43) KDM4EHTTKMT2AMRGPRX4BRAF
SCHEMBL30817711 0.74 BRAF (0.52) KDM4EHTTKMT2ABRAFRAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107072993-B Pharmaceutical containing sodium-dependent phosphate transporter inhibitor 中外制药株式会社 2021-02-12 CN disclosed