Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26924598 | 1.00 | TSHR (0.47) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL13737752 | 0.98 | TSHR (0.48) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL28715308 | 0.90 | TSHR (0.52) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL27166334 | 0.86 | TSHR (0.55) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL28715324 | 0.86 | TSHR (0.55) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL24835739 | 0.82 | TSHR (0.50) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL30552236 | 0.82 | TSHR (0.50) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL31591142 | 0.82 | TSHR (0.50) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL19369844 | 0.79 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19369592 | 0.79 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103074-A | Cytotoxic targeting chimeras for CCR2 expressing cells | 葛兰素史克知识产权发展有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-110603330-B | Oligonucleotide derivative or salt thereof | 协和麒麟株式会社 | 2023-09-05 | — | — | CN | disclosed |
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |