Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.63 |
| ▸ | SIK2 | Q9H0K1 | 11/20 | 0.62 |
| ▸ | SIK3 | Q9Y2K2 | 11/20 | 0.62 |
| ▸ | ABL1 | P00519 | 12/20 | 0.62 |
| ▸ | SRC | P12931 | 6/20 | 0.62 |
| ▸ | SIK1 | P57059 | 9/20 | 0.62 |
| ▸ | BCR | P11274 | 3/20 | 0.61 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.61 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523154 | 0.96 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28519140 | 0.94 | SIK2 (0.59) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28534533 | 0.92 | ABL1 (0.65) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1147166 | 0.88 | HDAC3 (0.81) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28528544 | 0.88 | SIK2 (0.80) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL29729006 | 0.84 | SIK2 (0.81) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28519609 | 0.84 | SIK2 (0.77) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13637397 | 0.84 | HDAC1 (0.68) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28519616 | 0.82 | SIK2 (0.75) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL22452260 | 0.81 | HDAC3 (0.77) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727981-B | Kinase inhibitor, preparation, pharmaceutical composition and application thereof | 湖南华纳大药厂股份有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-113727981-A | Kinase inhibitor, preparation, pharmaceutical composition and application thereof | 湖南华纳大药厂股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-112409349-A | Kinase inhibitor, preparation, pharmaceutical composition and application thereof | 湖南华纳大药厂股份有限公司 | 2021-02-26 | — | — | CN | disclosed |