Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253006 | 0.84 | NR4A1 (0.61) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL28589368 | 0.82 | NR4A1 (0.59) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL27518457 | 0.81 | NR4A1 (0.57) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL27360130 | 0.81 | NR4A1 (0.57) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL2501128 | 0.79 | NR4A1 (0.55) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL9415837 | 0.78 | NR4A1 (0.53) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL7734634 | 0.77 | KMT2A (0.55) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL29381201 | 0.75 | KDM4E (0.68) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL43084 | 0.75 | KDM4E (0.68) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL244802 | 0.74 | CDC25B (0.80) | NR4A1NR4A2NR4A3MMP3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159569-A | Use of apoptosis inhibitor 5 (API 5) for epithelial remodeling | 纽约大学 | 2024-06-07 | — | — | CN | claimed |
| CN-115989042-A | Copper-containing theranostic compounds and methods of use | 康奈尔大学 | 2023-04-18 | — | — | CN | claimed |
| CN-119072485-A | Conjugates, compositions and methods for hydroxyapatite targeted imaging and therapy | 普渡研究基金会 | 2024-12-03 | — | — | CN | disclosed |
| CN-118159569-A | Use of apoptosis inhibitor 5 (API 5) for epithelial remodeling | 纽约大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-115989042-A | Copper-containing theranostic compounds and methods of use | 康奈尔大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-115243704-A | Treatment of liver and cardiovascular disorders | 生命搜索 | 2022-10-25 | — | — | CN | disclosed |
| CN-113710246-A | HSP90 binding conjugates and formulations thereof | 塔弗达治疗有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-113056288-A | Macrocyclic complexes of radionuclides and their use in radiotherapy of cancer | 康奈尔大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-112074288-A | HSP 90-targeting conjugates and formulations thereof | 塔弗达治疗有限公司 | 2020-12-11 | — | — | CN | disclosed |