Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.69 |
| ▸ | GSK3B | P49841 | 2/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.68 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CA12 | O43570 | 3/20 | 0.63 |
| ▸ | CA9 | Q16790 | 3/20 | 0.63 |
| ▸ | CA5A | P35218 | 2/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13453289 | 0.92 | FLT3 (0.81) | FLT3GSK3BPTGS2PTGS1CA1 | |
| SCHEMBL18737325 | 0.84 | FLT3 (0.69) | FLT3GSK3BPTGS2PTGS1CA1 | |
| SCHEMBL18031103 | 0.84 | FLT3 (0.69) | FLT3GSK3BPTGS2PTGS1CA1 | |
| SCHEMBL28330114 | 0.83 | FLT3 (0.73) | FLT3GSK3BPTGS2PTGS1CA1 | |
| SCHEMBL12522541 | 0.83 | FLT3 (0.73) | FLT3GSK3BPTGS2PTGS1CA1 | |
| SCHEMBL12420373 | 0.83 | FLT3 (0.69) | FLT3PTGS2PTGS1CA1CA2 | |
| SCHEMBL12420378 | 0.83 | FLT3 (0.69) | FLT3GSK3BPTGS2PTGS1CA1 | |
| SCHEMBL28121993 | 0.82 | FLT3 (0.72) | FLT3GSK3BPTGS2PTGS1CA1 | |
| SCHEMBL28516006 | 0.81 | FLT3 (0.66) | FLT3GSK3BPTGS2PTGS1CA1 | |
| SCHEMBL12573171 | 0.81 | FLT3 (0.66) | FLT3GSK3BPTGS2PTGS1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341444-B | 3- (2, 3-dihydropyrrole) indole compound and preparation method thereof | 常州大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-112341444-A | 3- (2, 3-dihydropyrrole) indole compound and preparation method thereof | 常州大学 | 2021-02-09 | — | — | CN | disclosed |