Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.51 |
| ▸ | KDR | P35968 | 13/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KIF5B | P33176 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522414 | 0.94 | EGFR (0.49) | EGFRKDRERBB2RETKIF5B | |
| SCHEMBL28908558 | 0.94 | EGFR (0.49) | EGFRKDRERBB2RETKIF5B | |
| SCHEMBL28527723 | 0.93 | RET (0.54) | EGFRKDRERBB2RETKIF5B | |
| SCHEMBL28522006 | 0.93 | RET (0.54) | EGFRKDRERBB2RETKIF5B | |
| SCHEMBL28518401 | 0.89 | EGFR (0.53) | EGFRKDRERBB2 | |
| SCHEMBL28522509 | 0.86 | KDR (0.63) | EGFRKDRRETKIF5B | |
| SCHEMBL28522716 | 0.85 | KDR (0.50) | EGFRKDRERBB2 | |
| SCHEMBL28521215 | 0.85 | EGFR (0.54) | EGFRKDRERBB2RETKIF5B | |
| SCHEMBL28529605 | 0.84 | EGFR (0.53) | EGFRKDRERBB2 | |
| SCHEMBL28518388 | 0.84 | RET (0.55) | EGFRKDRERBB2RETKIF5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808031-B | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-111808031-A | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2020-10-23 | — | — | CN | disclosed |