SCHEMBL28516756

SCHEMBL28516756

c1ccc(N(c2ccc3ccccc3c2)c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ATM Q13315 1/20 0.50
PER2 O15055 1/20 0.36
CRY1 Q16526 1/20 0.36
CRY2 Q49AN0 1/20 0.36
ALDH1A1 P00352 3/20 0.34
TSHR P16473 1/20 0.34
MAPK8 P45983 1/20 0.34
SIGMAR1 Q99720 1/20 0.33
MAPT P10636 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PTGER4 P35408 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PDE7A Q13946 1/20 0.33
BACE1 P56817 1/20 0.33
HSD17B10 Q99714 1/20 0.33
F2 P00734 1/20 0.32
F10 P00742 1/20 0.32
PRSS1 P07477 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12559396 1.00 KDM4E (0.50) KDM4EL3MBTL1ATMPER2CRY1
SCHEMBL12559390 1.00 KDM4E (0.50) KDM4EL3MBTL1ATMPER2CRY1
SCHEMBL12242939 0.99 KDM4E (0.51) KDM4EL3MBTL1ATMPER2CRY1
SCHEMBL8928247 0.97 KDM4E (0.53) KDM4EL3MBTL1ATMPER2CRY1
SCHEMBL17740670 0.97 KDM4E (0.53) KDM4EL3MBTL1ATMPER2CRY1
SCHEMBL10087124 0.97 KDM4E (0.53) KDM4EL3MBTL1ATMPER2CRY1
SCHEMBL12559427 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMALDH1A1TSHR
SCHEMBL12559426 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMALDH1A1TSHR
SCHEMBL10087123 0.95 KDM4E (0.47) KDM4EL3MBTL1ATMPER2CRY1
SCHEMBL10087127 0.95 KDM4E (0.47) KDM4EL3MBTL1ATMPER2CRY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961167-B Organic compound, light-emitting element, light-emitting device, electronic device, display device, and lighting device 株式会社半导体能源研究所 2024-06-07 CN disclosed
CN-115677715-A Organic compound, light-emitting element, light-emitting device, electronic device, display device, and lighting device 株式会社半导体能源研究所 2023-02-03 CN disclosed
CN-109153685-B Organic compound, light-emitting element, light-emitting device, electronic device, display device, and lighting device 株式会社半导体能源研究所 2022-11-22 CN disclosed
CN-112961167-A Organic compound, light-emitting element, light-emitting device, electronic device, display device, and lighting device 株式会社半导体能源研究所 2021-06-15 CN disclosed
CN-109928980-B Organic compound, light-emitting element, light-emitting device, electronic device, display device, and lighting device 株式会社半导体能源研究所 2021-03-02 CN disclosed