Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.54 |
| ▸ | BACE1 | P56817 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608939 | 0.89 | ERN1 (0.58) | ERN1BACE1ACHEALDH1A1TRIM24 | |
| SCHEMBL8782875 | 0.86 | HDAC8 (0.59) | ERN1BACE1ACHEALDH1A1TRIM24 | |
| SCHEMBL3677398 | 0.84 | ERN1 (0.56) | ERN1BACE1ACHEALDH1A1TRIM24 | |
| SCHEMBL15959114 | 0.84 | MAOB (0.51) | ERN1BACE1ACHEALDH1A1TRIM24 | |
| SCHEMBL5515488 | 0.83 | ERN1 (0.51) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL14642539 | 0.83 | ERN1 (0.51) | ERN1BACE1ACHEALDH1A1TRIM24 | |
| SCHEMBL14840763 | 0.83 | ERN1 (0.51) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL1983140 | 0.83 | HDAC3 (0.52) | ERN1BACE1ACHEALDH1A1TRIM24 | |
| SCHEMBL16397775 | 0.83 | GSTP1 (0.53) | ERN1ALDH1A1HDAC8CYP1A2CYP2C9 | |
| SCHEMBL23191292 | 0.81 | GSTP1 (0.62) | ERN1BACE1ACHEALDH1A1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003320-A | Preparation method of phenanthridine compound | 武汉理工大学深圳研究院 | 2023-04-25 | — | — | CN | disclosed |
| CN-110194744-B | Compound for inhibiting beta-amyloid protein generation and preparation method and application thereof | 云南大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-108047048-B | Phenylpropanoate compound and preparation method and application thereof | 苏州沪云肿瘤研究中心股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-110194744-A | A kind of compound and its preparation method and application for inhibiting beta-amyloid protein to generate | 云南大学 | 2019-09-03 | — | — | CN | disclosed |
| CN-102838635-B | A kind of method preparing 2-oxa-phospholane | SUZHOU UNIVERSITY (CN) | 2015-11-18 | — | — | CN | disclosed |
| CN-102838633-B | Method for preparing gamma-oxophosphonate | UNIV SOOCHOW | 2015-03-25 | — | — | CN | disclosed |
| CN-102838633-A | Method for preparing gamma-oxophosphonate | UNIV SOOCHOW | 2012-12-26 | — | — | CN | disclosed |
| CN-102838635-A | Method for preparing dioxaphospholane | UNIV SOOCHOW | 2012-12-26 | — | — | CN | disclosed |