Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23751098 | 0.76 | HDAC11 (0.45) | HDAC11HDAC8 | |
| SCHEMBL28512020 | 0.75 | HDAC11 (0.58) | HDAC11HDAC8 | |
| SCHEMBL21496850 | 0.75 | HDAC11 (0.46) | HDAC11HDAC8 | |
| SCHEMBL21496739 | 0.75 | HDAC11 (0.57) | HDAC11HDAC8 | |
| SCHEMBL30038649 | 0.75 | HDAC11 (0.57) | HDAC11HDAC8 | |
| SCHEMBL21500458 | 0.68 | HDAC11 (0.57) | HDAC11HDAC8 | |
| SCHEMBL30040030 | 0.68 | HDAC11 (0.57) | HDAC11HDAC8 | |
| SCHEMBL28519553 | 0.68 | HDAC11 (0.43) | HDAC11HDAC8 | |
| SCHEMBL21496684 | 0.64 | HDAC11 (0.37) | HDAC11 | |
| SCHEMBL28511639 | 0.64 | HDAC11 (0.58) | HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292370-A | Isoindolines as HDAC inhibitors | 瓦洛早期发现股份有限公司 | 2021-01-29 | — | — | CN | disclosed |