Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL189681 | 0.79 | MAPT (0.61) | KITGBA1ACHEOPRM1OPRD1 | |
| SCHEMBL15566743 | 0.73 | GPR6 (0.59) | GBA1OPRM1OPRD1OGFRL1 | |
| SCHEMBL24970264 | 0.72 | MEN1 (0.47) | KITGPR119DDB1CRBNSTS | |
| SCHEMBL30903380 | 0.72 | MEN1 (0.47) | KITGPR119DDB1CRBNSTS | |
| SCHEMBL30819461 | 0.72 | GBA1 (0.56) | KITGBA1ACHEOPRM1OPRD1 | |
| SCHEMBL24951551 | 0.72 | GBA1 (0.56) | KITGBA1ACHEOPRM1OPRD1 | |
| SCHEMBL4513123 | 0.71 | NPY5R (0.48) | GPR119NAMPTCKS1BSKP1SKP2 | |
| SCHEMBL30261848 | 0.70 | DDB1 (0.62) | MAP4K4GPR119CKS1BSKP1SKP2 | |
| SCHEMBL28956351 | 0.70 | DDB1 (0.62) | MAP4K4GPR119CKS1BSKP1SKP2 | |
| SCHEMBL16818116 | 0.70 | GPR6 (0.52) | KITGBA1ACHEOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313228-A | Novel heteroaryl heterocyclyl compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2021-02-02 | — | — | CN | disclosed |