SCHEMBL28518339

SCHEMBL28518339

Nc1cc(N)cc(Cl)c1.c1ncncn1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.63
TP53 P04637 1/20 0.63
ALDH1A1 P00352 6/20 0.40
TSHR P16473 4/20 0.37
THRB P10828 1/20 0.36
HSP90AA1 P07900 1/20 0.35
ALOX15 P16050 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GAA P10253 1/20 0.30
CASP1 P29466 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221178 0.85
Cyanide SCHEMBL28159670 0.82 CYP3A4 (0.71) CYP3A4TP53ALDH1A1TSHRTHRB
Ammonia Solution, Strong SCHEMBL27616474 0.82 CYP3A4 (0.80) CYP3A4TP53ALDH1A1TSHRTHRB
Hydrochloric Acid SCHEMBL8640357 0.82 CYP3A4 (0.80) CYP3A4TP53ALDH1A1TSHRTHRB
Hydrochloric Acid SCHEMBL8640352 0.82 CYP3A4 (0.80) CYP3A4TP53ALDH1A1TSHRTHRB
SCHEMBL127074 0.78
Hydrochloric Acid SCHEMBL4371942 0.76 CYP3A4 (0.93) CYP3A4TP53ALDH1A1TSHRTHRB
Hydrochloric Acid SCHEMBL10975110 0.76 CYP3A4 (0.93) CYP3A4TP53ALDH1A1TSHRTHRB
Nitrogen SCHEMBL28728934 0.73 CYP3A4 (0.87) CYP3A4TP53ALDH1A1TSHRTHRB
SCHEMBL22082751 0.73 CYP3A4 (0.43) CYP3A4TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109627490-B Red organic colorant applied to resin coloring and preparation method thereof 沈阳化工研究院有限公司 2021-02-05 CN disclosed