Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL18813849 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNSLC7A5TP53 | |
| Acetic Acid SCHEMBL530185 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNSLC7A5TP53 | |
| Acetic Acid SCHEMBL1367670 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNSLC7A5TP53 | |
| Acetic Acid SCHEMBL28926333 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNSLC7A5TP53 | |
| Acetic Acid SCHEMBL28664367 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNSLC7A5TP53 | |
| Acetic Acid SCHEMBL9151775 | 0.88 | FFAR3 (0.58) | FFAR3LCKFYNSLC7A5TP53 | |
| SCHEMBL289711 | 0.88 | — | — | |
| Acetic Acid SCHEMBL10589745 | 0.84 | — | — | |
| SCHEMBL27573942 | 0.84 | — | — | |
| SCHEMBL27559326 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112322103-B | Rare earth modification (MnCoY)3O4Method for producing a dense coating | 昆明理工大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-112322103-A | Rare earth modification (MnCOY)3O4Method for producing a dense coating | 昆明理工大学 | 2021-02-05 | — | — | CN | disclosed |