Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25316221 | 1.00 | MEN1 (0.44) | MEN1KMT2AHTR2AHTR2CSLC6A4 | |
| SCHEMBL31444311 | 0.95 | HTR2A (0.41) | MEN1KMT2AHTR2AHTR2CSLC6A4 | |
| SCHEMBL31444461 | 0.94 | HTR2A (0.40) | MEN1KMT2AHTR2AHTR2CSLC6A4 | |
| SCHEMBL2239285 | 0.87 | MEN1 (0.41) | MEN1KMT2ASLC6A4KCNH2PDCD1LG2 | |
| SCHEMBL2239281 | 0.87 | MEN1 (0.41) | MEN1KMT2ASLC6A4KCNH2PDCD1LG2 | |
| Hydrochloric Acid SCHEMBL15017218 | 0.85 | OPRL1 (0.40) | MEN1KMT2AHTR2AHTR2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL15017219 | 0.85 | OPRL1 (0.40) | MEN1KMT2AHTR2AHTR2CSLC6A4 | |
| SCHEMBL3333995 | 0.83 | MEN1 (0.46) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL19599013 | 0.83 | MEN1 (0.46) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL28840097 | 0.83 | MEN1 (0.46) | MEN1KMT2AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |