Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.35 |
| ▸ | PDE4A | P27815 | 6/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.31 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825675 | 1.00 | ERN1 (0.36) | ERN1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2851968 | 1.00 | ERN1 (0.36) | ERN1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2825592 | 0.93 | PDE4D (0.43) | ERN1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5116011 | 0.89 | PDE4D (0.36) | ERN1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5124265 | 0.89 | PDE4D (0.36) | ERN1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2265714 | 0.85 | ERN1 (0.36) | ERN1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2270155 | 0.85 | ERN1 (0.36) | ERN1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL14696696 | 0.85 | ERN1 (0.36) | ERN1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2264994 | 0.85 | ERN1 (0.36) | ERN1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2344026 | 0.80 | PDE4D (0.36) | ERN1PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846390-B1 | NOVEL 6-PYRIDYLPHENANTHRIDINES | NYCOMED GMBH (DE) | 2010-03-17 | — | — | EP | disclosed |