SCHEMBL28520151

SCHEMBL28520151

CC(C)(C)c1cc(C(OP(=O)(O)O[AlH2])c2cc(C(C)(C)C)cc(C(C)(C)C)c2)cc(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 5/20 0.38
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27190149 0.84 HMGCR (0.36) HMGCRGABRA1GABRB2
SCHEMBL29108863 0.83 HMGCR (0.41) HMGCRGABRA1GABRB2
SCHEMBL27171245 0.83 HMGCR (0.37) HMGCRGABRA1GABRB2
SCHEMBL25241826 0.81 HMGCR (0.41) HMGCRGABRA1GABRB2
SCHEMBL20299546 0.81 HMGCR (0.41) HMGCRGABRA1GABRB2
SCHEMBL20299555 0.81 HMGCR (0.41) HMGCRGABRA1GABRB2
SCHEMBL19858472 0.81 HMGCR (0.41) HMGCRGABRA1GABRB2
Zinc Ion SCHEMBL20299534 0.75 HMGCR (0.41) HMGCRGABRA1GABRB2
SCHEMBL20299511 0.75 HMGCR (0.41) HMGCRGABRA1GABRB2
Water SCHEMBL20299523 0.75 HMGCR (0.41) HMGCRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063895-A Extrusion-blowing transparent polypropylene resin and preparation method thereof 中国神华煤制油化工有限公司 2024-05-24 CN claimed
CN-118063895-A Extrusion-blowing transparent polypropylene resin and preparation method thereof 中国神华煤制油化工有限公司 2024-05-24 CN disclosed
CN-111601844-B Polymer composition with improved paint adhesion 博里利斯股份公司 2024-01-30 CN disclosed
CN-117124498-A Preparation method of reinforced flame-retardant PBT/PET alloy with stable thermal deformation temperature 烟台佳合塑胶科技有限公司 2023-11-28 CN disclosed
CN-117043255-A Polypropylene composition for cable insulation 博里利斯股份公司 2023-11-10 CN disclosed
CN-111372988-B Fiber reinforced polypropylene composition 北欧化工公司 2023-09-15 CN disclosed
CN-113330058-A Nucleating agent composition, olefin resin composition, molded article thereof, and method for producing olefin resin composition 株式会社ADEKA 2021-08-31 CN disclosed
CN-107417859-B High-melt-strength polypropylene grafted by heteroaromatic ring derivative and preparation method thereof 中国石油化工股份有限公司 2021-02-26 CN disclosed