Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.43 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CIT | O14578 | 1/20 | 0.41 |
| ▸ | MUSK | O15146 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23045050 | 0.90 | KDM4E (0.51) | MAPK14MCHR1 | |
| SCHEMBL4252948 | 0.88 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11TNF | |
| SCHEMBL23045048 | 0.81 | HTT (0.51) | MAPK14 | |
| SCHEMBL5257397 | 0.79 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11TNF | |
| SCHEMBL6162405 | 0.79 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11TNF | |
| SCHEMBL6160279 | 0.77 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11TNF | |
| SCHEMBL1599976 | 0.76 | MAPK14 (0.61) | MAPK14MCHR1MAPK13MAPK12MAPK11 | |
| SCHEMBL23045029 | 0.74 | HDAC1 (0.41) | MEN1KMT2ACDK8 | |
| Hydrochloric Acid SCHEMBL6250129 | 0.74 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11TNF | |
| SCHEMBL14272143 | 0.73 | MAPK14 (0.75) | MAPK14MCHR1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526881-B | Naphthylamine compound and biologically acceptable salt thereof, and preparation method and application thereof | 河南省锐达医药科技有限公司 | 2020-09-22 | — | — | CN | disclosed |