Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26641014 | 0.96 | TDP1 (0.45) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL21070840 | 0.91 | TDP1 (0.50) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL31395837 | 0.91 | CA1 (0.46) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL21070189 | 0.91 | CA1 (0.46) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL14745412 | 0.91 | CA1 (0.46) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL14740858 | 0.91 | CA1 (0.46) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL21070363 | 0.91 | CA1 (0.46) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL15969366 | 0.91 | CA1 (0.46) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL14744716 | 0.91 | CA1 (0.46) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL499627 | 0.91 | CA1 (0.46) | TDP1CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |