SCHEMBL28521

SCHEMBL28521

CC([O])(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80383 0.88
SCHEMBL6594929 0.78
SCHEMBL10840505 0.78
SCHEMBL4950749 0.78
SCHEMBL775219 0.78
SCHEMBL142176 0.78
SCHEMBL4950529 0.78
SCHEMBL337086 0.78
SCHEMBL1187296 0.78
SCHEMBL2410181 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3409 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024125668-A1 HETEROCYCLIC SUBSTITUTED PENTA-SIX-MEMBERED HETEROARYL DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION AND PREPARATION METHOD THEREFOR 上海海雁医药科技有限公司 2024-06-20 WO claimed
CN-118159530-A Compounds for the treatment of pain, in particular neuropathic pain and/or other diseases or disorders associated with AT2R and/or AT2R mediated signalling 康福治疗有限公司 2024-06-07 CN claimed
EP-4377307-A1 COMPOUNDS FOR THE TREATMENT OF PAIN, IN PARTICULAR NEUROPATHIC PAIN, AND/OR OTHER DISEASES OR DISORDERS THAT ARE ASSOCIATED WITH AT2R AND/OR AT2R MEDIATED SIGNALING Confo Therapeutics N.V. (BE) 2024-06-05 EP claimed
WO-2024104344-A1 QUINOLINECARBOXYLIC ACID DERIVATIVE AND USE THEREOF 沈阳中化农药化工研发有限公司 2024-05-23 WO claimed
CN-118047721-A Quinoline carboxylic acid derivative and application thereof 沈阳中化农药化工研发有限公司 2024-05-17 CN claimed
WO-2024102849-A1 BIFUNCTIONAL COMPOUNDS CONTAINING 2,5-SUBSTITUTED PYRIMIDINE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY NIKANG THERAPEUTICS, INC. (US) 2024-05-16 WO claimed
WO-2024102026-A1 INHIBITORS OF HUMAN ALDOSTERONE SYNTHASE (CYP11B2) «TARGET MEDICALS» LIMITED LIABILITY COMPANY (RU) 2024-05-16 WO claimed
WO-2024084360-A1 PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 (PNPLA3) MODIFIERS PFIZER INC. (US) 2024-04-25 WO claimed
EP-4334315-A1 ALKYLAMIDE SUBSTITUTED, ANNULATED IMIDAZOLES AND USE THEREOF AS INSECTICIDES Bayer Aktiengesellschaft (DE) 2024-03-13 EP claimed
US-20240076271-A1 KDM4 INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2024-03-07 US claimed
US-5708184-A HERBICIDES, SIMPLIFIED PROCESS BAYER AKTIENGESELLSCHAFT (DE) 1998-01-13 US claimed
CN-1153512-A Substituted pyrrolidones, thiazolidinones or oxazolidinones as herbicides ZENECA LTD (GB) 1997-07-02 CN claimed
EP-0763020-A1 SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES ZENECA LIMITED (GB) 1997-03-19 EP claimed
CN-1145068-A Substituted sulphonylaminocarbonyltriazolinones and their use as herbicides BAYER AG (DE) 1997-03-12 CN claimed
US-5610121-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-11 US claimed
WO-1995033719-A1 SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES ZENECA LIMITED (GB) 1995-12-14 WO claimed
EP-0280240-B1 Cephalosporin derivatives, process for their preparation and antibacterial agents BANYU PHARMA CO LTD (JP) 1994-09-14 EP claimed
US-5049665-A Cephalosporin derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-09-17 US claimed
US-4918070-A Antibiotics BANYU PHARMACEUTICAL CO., LTD. (JP) 1990-04-17 US claimed
US-3960936-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, SKIN DISORDERS SYNTEX CORPORATION (PM) 1976-06-01 US claimed