Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 18/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.60 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28685442 | 0.82 | GRIN2B (0.53) | GRIN2BGRIN1PIK3C3 | |
| SCHEMBL28511559 | 0.81 | GRIN2B (0.60) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL28523430 | 0.81 | GRIN2B (0.62) | GRIN2BGRIN1 | |
| SCHEMBL28511602 | 0.80 | GRIN2B (0.53) | GRIN2BGRIN1 | |
| SCHEMBL21611130 | 0.77 | GRIN2B (0.61) | GRIN2BGRIN1 | |
| SCHEMBL18363585 | 0.75 | GRIN2B (1.00) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL18363247 | 0.72 | GRIN2B (1.00) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL18363248 | 0.70 | GRIN2B (1.00) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL22775590 | 0.69 | GRIN2B (0.71) | GRIN2BGRIN1 | |
| SCHEMBL29550475 | 0.69 | GRIN2B (0.71) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026094-B | Substituted 4-azaindoles and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2021-02-09 | — | — | CN | claimed |