Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | PLCG2 | P16885 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | PYGM | P11217 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277489 | 0.86 | APEX1 (0.70) | APEX1MAPTMAPK1PLCG2NPC1 | |
| SCHEMBL1016404 | 0.83 | APEX1 (0.65) | APEX1MAPTMAPK1PLCG2NPC1 | |
| SCHEMBL1277212 | 0.82 | APEX1 (1.00) | APEX1MAPTMAPK1PLCG2NPC1 | |
| SCHEMBL5268675 | 0.82 | APEX1 (1.00) | APEX1MAPTMAPK1PLCG2NPC1 | |
| SCHEMBL1653052 | 0.81 | APEX1 (0.76) | APEX1MAPTMAPK1PLCG2NPC1 | |
| SCHEMBL6215530 | 0.78 | APEX1 (0.70) | APEX1MAPTMAPK1PLCG2NPC1 | |
| SCHEMBL1654091 | 0.77 | APEX1 (0.69) | APEX1MAPTMAPK1PLCG2NPC1 | |
| SCHEMBL25191965 | 0.76 | APEX1 (0.56) | APEX1MAPTMAPK1PLCG2NPC1 | |
| SCHEMBL3726872 | 0.75 | APEX1 (0.82) | APEX1MAPTMAPK1PLCG2NPC1 | |
| SCHEMBL27942805 | 0.73 | APEX1 (0.68) | APEX1MAPTMAPK1PLCG2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321478-A | Synthetic method of 4-fluoro-7-nitroindole or derivative thereof | 上海代为化学科技有限公司 | 2021-02-05 | — | — | CN | disclosed |