SCHEMBL28523360

SCHEMBL28523360

CCc1cc(S(=O)(=O)Nc2cscn2)c(F)cc1N(C)C1CCNC1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 20/20 0.64
SCN1A P35498 15/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28907844 0.92 SCN8A (0.61) SCN8ASCN1A
SCHEMBL28525243 0.90 SCN8A (0.64) SCN8ASCN1A
SCHEMBL19627655 0.89 SCN8A (0.67) SCN8ASCN1A
SCHEMBL28519890 0.89 SCN8A (0.67) SCN8ASCN1A
SCHEMBL19627698 0.88 SCN1A (0.67) SCN8ASCN1A
SCHEMBL19614184 0.88 SCN1A (0.67) SCN8ASCN1A
SCHEMBL19614185 0.88 SCN1A (0.67) SCN8ASCN1A
Hydrochloric Acid SCHEMBL19613672 0.88 SCN1A (0.66) SCN8ASCN1A
Hydrochloric Acid SCHEMBL19613675 0.88 SCN1A (0.66) SCN8ASCN1A
SCHEMBL28527159 0.87 SCN8A (0.64) SCN8ASCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109526219-B Benzenesulfonamides and their use as therapeutic agents 泽农医药公司 2021-03-12 CN disclosed