SCHEMBL28523639

SCHEMBL28523639

CCC/C=C\C#CC=C(OCCCCCCC)OCCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.42
PPARG P37231 1/20 0.40
NAAA Q02083 1/20 0.37
HMGCR P04035 4/20 0.36
FAAH O00519 1/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
EPHX1 P07099 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR2 Q9HBW0 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35
ATM Q13315 1/20 0.34
TSHR P16473 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21065507 0.69 HCAR2 (0.71) HCAR2NAAAEPHX1ATMTSHR
SCHEMBL18339407 0.69 HCAR2 (0.71) HCAR2NAAAEPHX1ATMTSHR
SCHEMBL18339405 0.69 HCAR2 (0.71) HCAR2NAAAEPHX1ATMTSHR
SCHEMBL11825918 0.69 HCAR2 (0.71) HCAR2NAAAEPHX1ATMTSHR
SCHEMBL11825924 0.69 HCAR2 (0.71) HCAR2NAAAEPHX1ATMTSHR
SCHEMBL16161115 0.68 HMGCR (0.52) HCAR2PPARGNAAAHMGCRFAAH
SCHEMBL16161104 0.68 HMGCR (0.52) HCAR2PPARGNAAAHMGCRFAAH
SCHEMBL16161664 0.68 HMGCR (0.52) HCAR2PPARGNAAAHMGCRFAAH
SCHEMBL17027690 0.66 HMGCR (0.63) PPARGHMGCR
SCHEMBL15420337 0.66 HMGCR (0.63) PPARGHMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112441895-B Dialkoxy alkadienyne compound, preparation method thereof and preparation method of dialkoxy alkadienyne aldehyde compound 信越化学工业株式会社 2024-01-23 CN disclosed
CN-112441895-A Dialkoxyl alkadienyne compound, preparation method thereof and preparation method of diene alkynal compound 信越化学工业株式会社 2021-03-05 CN disclosed