Fluoride

Fluoride

SCHEMBL28523973

F.F.F.Fc1ccccc1F

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.53
NFE2L2 Q16236 5/20 0.50
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
TAAR1 Q96RJ0 1/20 0.43
ALDH1A1 P00352 1/20 0.41
ALOX15 P16050 1/20 0.41
IDO1 P14902 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM1A O60341 2/20 0.38
KDM1B Q8NB78 1/20 0.38
MGLL Q99685 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45406 0.95
SCHEMBL29352330 0.95
SCHEMBL9062627 0.91
Water SCHEMBL27300480 0.91
Methane SCHEMBL27721780 0.91
Bromide SCHEMBL1357794 0.91
SCHEMBL28213020 0.91
SCHEMBL31435867 0.91
Lithium SCHEMBL31490346 0.91
Hydrogen Sulfide SCHEMBL28163250 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108409605-B Preparation method of 3, 4-difluorobenzonitrile 江苏丰山集团股份有限公司 2021-02-19 CN disclosed