SCHEMBL28524322

SCHEMBL28524322

OB(O)OB(O)Oc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 3/20 0.40
ORAI2 Q96SN7 3/20 0.40
ORAI3 Q9BRQ5 3/20 0.40
TRPV6 Q9H1D0 3/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
PCSK9 Q8NBP7 1/20 0.40
LTA4H P09960 3/20 0.38
TSHR P16473 1/20 0.38
CA5A P35218 2/20 0.36
CA5B Q9Y2D0 2/20 0.36
CA4 P22748 2/20 0.35
CA6 P23280 1/20 0.35
CA7 P43166 1/20 0.35
ENPP2 Q13822 1/20 0.35
CA14 Q9ULX7 1/20 0.35
NR1H2 P55055 1/20 0.34
BAX Q07812 1/20 0.34
ALDH1A1 P00352 2/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1878004 0.85 CA1 (0.46) ORAI1ORAI2ORAI3TRPV6CA1
SCHEMBL26924654 0.83 ORAI1 (0.42) ORAI1ORAI2ORAI3TRPV6CA1
SCHEMBL9443206 0.82 CA1 (0.44) ORAI1ORAI2ORAI3TRPV6CA1
Ammonia Solution, Strong SCHEMBL9443078 0.80 CA1 (0.43) ORAI1ORAI2ORAI3TRPV6CA1
SCHEMBL9443233 0.80 CA1 (0.43) ORAI1ORAI2ORAI3TRPV6CA1
SCHEMBL9443046 0.80 CA1 (0.43) ORAI1ORAI2ORAI3TRPV6CA1
SCHEMBL28337059 0.79 CA1 (0.46) ORAI1ORAI2ORAI3TRPV6CA1
SCHEMBL78440 0.79 CA1 (0.46) ORAI1ORAI2ORAI3TRPV6CA1
Benzene SCHEMBL28134938 0.79 CA1 (0.46) ORAI1ORAI2ORAI3TRPV6CA1
SCHEMBL28102434 0.79 CA1 (0.46) ORAI1ORAI2ORAI3TRPV6CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109988265-B Preparation method of self-repairing hydrogel 中国科学院深圳先进技术研究院 2021-03-02 CN claimed
CN-109012747-B Application of copper (I) coordination polymer 苏州大学 2021-02-12 CN claimed
CN-109988265-B Preparation method of self-repairing hydrogel 中国科学院深圳先进技术研究院 2021-03-02 CN disclosed