Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Crisugabalin SCHEMBL19982340 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 | |
| Crisugabalin SCHEMBL19982295 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 | |
| Crisugabalin SCHEMBL21144566 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 | |
| Crisugabalin SCHEMBL24631233 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 | |
| Crisugabalin SCHEMBL21144567 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 | |
| Crisugabalin SCHEMBL23080519 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 | |
| Crisugabalin SCHEMBL23071142 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 | |
| Crisugabalin SCHEMBL23080592 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 | |
| Crisugabalin SCHEMBL21621701 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 | |
| Crisugabalin SCHEMBL19982362 | 1.00 | POLB (0.35) | POLBUSP2ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384493-A | Process for the preparation of fused tricyclic gamma-amino acid derivatives and intermediates | 四川海思科制药有限公司 | 2021-02-19 | — | — | CN | disclosed |