Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526329 | 0.82 | ABL1 (0.49) | ABL1 | |
| SCHEMBL30046660 | 0.72 | ABL1 (0.59) | ABL1 | |
| SCHEMBL22939371 | 0.72 | ABL1 (0.59) | ABL1 | |
| SCHEMBL30046925 | 0.72 | ABL1 (0.53) | ABL1 | |
| SCHEMBL22939415 | 0.72 | ABL1 (0.53) | ABL1 | |
| SCHEMBL22939435 | 0.71 | ABL1 (0.49) | ABL1 | |
| SCHEMBL30046697 | 0.71 | ABL1 (0.49) | ABL1 | |
| SCHEMBL28518670 | 0.71 | ABL1 (0.46) | ABL1 | |
| SCHEMBL28525027 | 0.71 | ABL1 (0.48) | ABL1 | |
| SCHEMBL22938434 | 0.67 | ABL1 (0.52) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300129-B | Heterocyclic compounds as BCR-ABL inhibitors | 苏州亚盛药业有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-112300129-A | Heterocyclic compounds as BCR-ABL inhibitors | 苏州亚盛药业有限公司 | 2021-02-02 | — | — | CN | disclosed |