Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | POLB | P06746 | 6/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | GLA | P06280 | 2/20 | 0.73 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.73 |
| ▸ | PPARG | P37231 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.73 |
| ▸ | EIF4A1 | P60842 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703050 | 1.00 | KAT8 (0.76) | KAT8ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL28514597 | 0.87 | KAT8 (0.80) | KAT8ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL29703004 | 0.87 | KAT8 (0.80) | KAT8ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL13856164 | 0.85 | KDM4E (1.00) | KAT8ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL29703163 | 0.85 | KDM4E (1.00) | KAT8ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL14966520 | 0.83 | KAT8 (0.78) | KAT8ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL29702983 | 0.83 | KAT8 (0.78) | KAT8ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL28520535 | 0.81 | PTPN22 (0.64) | KAT8ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL29702976 | 0.81 | PTPN22 (0.64) | KAT8ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL19016221 | 0.79 | MEN1 (0.64) | ALDH1A1HPGDEIF4A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321571-B | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-112321571-A | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2021-02-05 | — | — | CN | disclosed |