SCHEMBL2852509

SCHEMBL2852509

O=C([C@@H]1C[C@H](N2CCC(c3ncsc3-c3ccccc3)CC2)CN1)N1CCSC1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2854199 0.89 DPP4 (0.63) DPP4
SCHEMBL2857079 0.85 DPP4 (0.68) DPP4
SCHEMBL2860379 0.83 DPP4 (0.68) DPP4
Hydrochloric Acid SCHEMBL2710769 0.81 DPP4 (0.98) DPP4
SCHEMBL2860337 0.80 DPP4 (0.66) DPP4
SCHEMBL2862064 0.79 DPP4 (0.69) DPP4
Hydrochloric Acid SCHEMBL2708942 0.78 DPP4 (0.71) DPP4
SCHEMBL2861999 0.78 DPP4 (0.65) DPP4
SCHEMBL2857150 0.77 DPP4 (0.61) DPP4
SCHEMBL2856719 0.77 DPP4 (0.75) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7790725-B2 Thiazolidine derivatives and medicinal use thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-09-07 US disclosed