Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 15/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 15/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 15/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 15/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 15/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 15/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 15/20 | 0.79 |
| ▸ | HDAC9 | Q9UKV0 | 15/20 | 0.79 |
| ▸ | HDAC5 | Q9UQL6 | 15/20 | 0.79 |
| ▸ | NCOR2 | Q9Y618 | 15/20 | 0.79 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24754549 | 0.88 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28177353 | 0.88 | HDAC6 (0.80) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28176355 | 0.87 | HDAC6 (0.82) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28520186 | 0.84 | HDAC6 (0.81) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28531912 | 0.83 | HDAC6 (0.80) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28177348 | 0.79 | HDAC6 (0.80) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28534046 | 0.79 | HDAC1 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL3488100 | 0.79 | TP53 (0.49) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28536299 | 0.79 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28176349 | 0.78 | HDAC6 (0.83) | HDAC6HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107445896-B | Phenyl hydroxamic acid compound with anti-tumor activity and application thereof | 沈阳药科大学 | 2021-03-05 | — | — | CN | claimed |
| CN-107445896-B | Phenyl hydroxamic acid compound with anti-tumor activity and application thereof | 沈阳药科大学 | 2021-03-05 | — | — | CN | disclosed |