Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | NPY4R | P50391 | 14/20 | 0.52 |
| ▸ | NPY1R | P25929 | 8/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.52 |
| ▸ | NPY2R | P49146 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL29245680 | 0.94 | SLC7A5 (0.58) | SLC7A5NPY4RNPY1RNPY5RNPY2R | |
| Tyrosine SCHEMBL1551967 | 0.94 | SLC7A5 (0.61) | SLC7A5NPY4RNPY1RNPY5RNPY2R | |
| Tyrosine SCHEMBL28440222 | 0.92 | SLC7A5 (0.56) | SLC7A5NPY4RNPY1RNPY5RNPY2R | |
| Tyrosine SCHEMBL28465850 | 0.92 | SLC7A5 (0.56) | SLC7A5NPY4RNPY1RNPY5RNPY2R | |
| Tyrosine SCHEMBL11100070 | 0.91 | SLC7A5 (0.57) | SLC7A5NPY4RNPY1RNPY5RNPY2R | |
| Tyrosine SCHEMBL9745063 | 0.90 | SLC7A5 (0.56) | SLC7A5NPY4RNPY1RNPY5RNPY2R | |
| Tyrosine SCHEMBL21253169 | 0.90 | SLC7A5 (0.56) | SLC7A5NPY4RNPY1RNPY5RNPY2R | |
| Tyrosine SCHEMBL29144188 | 0.90 | SLC7A5 (0.56) | SLC7A5NPY4RNPY1RNPY5RNPY2R | |
| Tyrosine SCHEMBL27729866 | 0.90 | SLC7A5 (0.56) | SLC7A5NPY4RNPY1RNPY5RNPY2R | |
| Tyrosine SCHEMBL26115321 | 0.89 | NPY4R (0.60) | SLC7A5NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112625088-A | Preparation method and application of mussel ACE inhibitory peptide | 烟台市华昕生物医药科技有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-112481342-A | Method for synchronously preparing poultry heme and antioxidant blood peptide | 湖北省农业科学院农产品加工与核农技术研究所 | 2021-03-12 | — | — | CN | disclosed |