Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525542 | 1.00 | MAPT (0.50) | MAPTALDH1A1SIRT6GALR2MITF | |
| SCHEMBL29800663 | 1.00 | MAPT (0.50) | MAPTALDH1A1SIRT6GALR2MITF | |
| SCHEMBL28533547 | 1.00 | MAPT (0.50) | MAPTALDH1A1SIRT6GALR2MITF | |
| SCHEMBL29800608 | 1.00 | MAPT (0.50) | MAPTALDH1A1SIRT6GALR2MITF | |
| SCHEMBL28525541 | 1.00 | MAPT (0.50) | MAPTALDH1A1SIRT6GALR2MITF | |
| SCHEMBL28533550 | 1.00 | MAPT (0.50) | MAPTALDH1A1SIRT6GALR2MITF | |
| SCHEMBL29800273 | 0.90 | MAPT (0.52) | MAPTALDH1A1SIRT6GALR2MITF | |
| SCHEMBL29800266 | 0.90 | MAPT (0.52) | MAPTALDH1A1SIRT6GALR2MITF | |
| SCHEMBL28535079 | 0.88 | MAPT (0.44) | MAPTALDH1A1SIRT6LMNASMN1; SMN2 | |
| SCHEMBL28535077 | 0.88 | MAPT (0.44) | MAPTALDH1A1SIRT6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-A | Prophylactic or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2021-03-09 | — | — | CN | disclosed |