Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637685 | 0.85 | HTT (0.50) | HTT | |
| SCHEMBL3397059 | 0.69 | HTT (0.38) | HTT | |
| SCHEMBL28528015 | 0.69 | STAT3 (0.33) | — | |
| SCHEMBL31348595 | 0.67 | SRD5A1 (0.38) | — | |
| SCHEMBL244366 | 0.67 | HTT (0.46) | HTT | |
| SCHEMBL28562965 | 0.66 | HTT (0.49) | HTT | |
| SCHEMBL31382688 | 0.65 | — | — | |
| SCHEMBL11129232 | 0.64 | GAA (0.33) | — | |
| SCHEMBL10908000 | 0.63 | HTT (0.43) | HTT | |
| SCHEMBL28377991 | 0.63 | HTT (0.43) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480121-A | Polycyclic derivative and preparation thereof | 四川海思科制药有限公司 | 2021-03-12 | — | — | CN | disclosed |