Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521778 | 0.86 | TSHR (0.37) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6339982 | 0.81 | KMT2A (0.42) | MAPTLMNANPSR1GLO1TDP1 | |
| SCHEMBL17193050 | 0.81 | KMT2A (0.42) | MAPTLMNANPSR1GLO1TDP1 | |
| SCHEMBL6339979 | 0.81 | KMT2A (0.42) | MAPTLMNANPSR1GLO1TDP1 | |
| SCHEMBL275028 | 0.81 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL275027 | 0.81 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL279188 | 0.81 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL9564470 | 0.81 | POLB (0.43) | MAPTALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL13417554 | 0.79 | MAPT (0.58) | MAPTALDH1A1LMNAGLO1KDM4E | |
| SCHEMBL3187242 | 0.79 | MAPT (0.58) | MAPTALDH1A1LMNAGLO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409332-B | Triazole derivative and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-112409332-A | Triazole derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2021-02-26 | — | — | CN | disclosed |