Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528149 | 1.00 | KMT2A (0.50) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL18428078 | 0.92 | POLB (0.55) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL18428075 | 0.92 | POLB (0.55) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL18472304 | 0.86 | KMT2A (0.48) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL28907026 | 0.83 | HDAC4 (0.53) | ALDH1A1HDAC4HDAC1HDAC3HDAC7 | |
| SCHEMBL28907024 | 0.83 | HDAC4 (0.53) | ALDH1A1HDAC4HDAC1HDAC3HDAC7 | |
| SCHEMBL28528156 | 0.82 | KMT2A (0.48) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL1688915 | 0.82 | AAK1 (0.56) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL28528158 | 0.82 | KMT2A (0.48) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL3222110 | 0.81 | SMN1; SMN2 (0.64) | KMT2AMEN1MAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026026-B | Beta-substituted beta-amino acids and analogs as chemotherapeutic agents and uses thereof | 夸德里加生物科学公司 | 2021-02-09 | — | — | CN | disclosed |