SCHEMBL28528178

SCHEMBL28528178

CCOC(OC)(OCC)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.39
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CES1 P23141 1/20 0.37
LMNA P02545 2/20 0.37
KIF11 P52732 2/20 0.36
ALDH1A1 P00352 2/20 0.35
TAAR1 Q96RJ0 1/20 0.35
ALOX15 P16050 1/20 0.35
EDNRB P24530 1/20 0.35
EDNRA P25101 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
GAA P10253 1/20 0.34
LTA4H P09960 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379267 0.89 KCNN4 (0.43) KCNN4MAPK1LMNAKIF11ALDH1A1
SCHEMBL28800774 0.86 KCNN4 (0.41) KCNN4MAPK1LMNAKIF11ALDH1A1
SCHEMBL9576889 0.86 KCNN4 (0.35) KCNN4MAPK1KDM4EMEN1KMT2A
SCHEMBL487231 0.81 MAPK1 (0.48) KCNN4MAPK1CES1ALDH1A1TAAR1
SCHEMBL474157 0.81 KCNN4 (0.38) KCNN4MAPK1LMNAKIF11ALDH1A1
SCHEMBL15356091 0.77 KCNN4 (0.38) KCNN4MAPK1KDM4EMEN1KMT2A
SCHEMBL27650370 0.77 MAPK1 (0.41) KCNN4MAPK1KDM4EMEN1KMT2A
SCHEMBL6270358 0.77 MAPK1 (0.44) KCNN4MAPK1CES1ALDH1A1TAAR1
SCHEMBL6155774 0.76 KCNN4 (0.44) KCNN4MAPK1KIF11ALDH1A1TAAR1
SCHEMBL27959771 0.75 CES1 (0.39) KCNN4MAPK1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107126660-B Composition containing fluoroketone 中化蓝天集团有限公司 2021-02-05 CN disclosed