Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7178049 | 0.91 | TSHR (0.36) | TSHRTHRBGGPS1 | |
| SCHEMBL5985729 | 0.88 | — | — | |
| SCHEMBL5815638 | 0.88 | — | — | |
| SCHEMBL5810097 | 0.88 | — | — | |
| SCHEMBL10467193 | 0.88 | — | — | |
| SCHEMBL8994334 | 0.88 | — | — | |
| SCHEMBL5984571 | 0.88 | — | — | |
| SCHEMBL6241315 | 0.86 | — | — | |
| SCHEMBL1116256 | 0.85 | TSHR (0.44) | TSHRTHRBGGPS1 | |
| SCHEMBL1116285 | 0.85 | TSHR (0.44) | TSHRTHRBGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071492-B | Azabicyclo-substituted triazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-02-26 | — | — | CN | disclosed |