Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | DTYMK | P23919 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686065 | 1.00 | KDM4E (0.49) | KDM4EDTYMKKMT2AMEN1HTT | |
| SCHEMBL3512088 | 0.89 | AKR1C3 (0.46) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL30686032 | 0.88 | MAPT (0.47) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL28528923 | 0.88 | MAPT (0.47) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL268658 | 0.88 | TDP1 (0.55) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL26343197 | 0.87 | DTYMK (0.50) | KDM4EDTYMKKMT2AMEN1HTT | |
| SCHEMBL2155062 | 0.87 | MAPT (0.63) | KDM4EDTYMKKMT2AMEN1HTT | |
| SCHEMBL8381314 | 0.87 | MAPT (0.56) | KDM4EDTYMKKMT2AMEN1HTT | |
| SCHEMBL21707908 | 0.86 | TSHR (0.48) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL8872227 | 0.84 | MAPT (0.61) | KDM4EDTYMKKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409332-B | Triazole derivative and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-112409332-A | Triazole derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2021-02-26 | — | — | CN | disclosed |