Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528596 | 1.00 | MEN1 (0.56) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL16517582 | 0.89 | MEN1 (0.54) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL28526406 | 0.89 | TDP1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL28526408 | 0.89 | TDP1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL21384171 | 0.84 | MEN1 (0.48) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL22711096 | 0.81 | MEN1 (0.45) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL15297619 | 0.81 | MEN1 (0.45) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL22711273 | 0.81 | MEN1 (0.45) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL10639200 | 0.79 | MEN1 (0.71) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL8183776 | 0.79 | MEN1 (0.61) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236161-A | Modulators of G protein-coupled receptors | 卡莫特治疗学股份有限公司 | 2021-01-15 | — | — | CN | disclosed |