Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 6/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 7/20 | 0.43 |
| ▸ | F2R | P25116 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183705 | 1.00 | HTRA1 (0.48) | HTRA1RORCP2RY14TACR1F2R | |
| SCHEMBL24645690 | 1.00 | HTRA1 (0.48) | HTRA1RORCP2RY14TACR1F2R | |
| SCHEMBL28534685 | 0.89 | P2RY14 (0.45) | HTRA1RORCP2RY14TACR1MAPT | |
| SCHEMBL6184744 | 0.88 | HTRA1 (0.46) | HTRA1RORCP2RY14TACR1F2R | |
| SCHEMBL25365634 | 0.88 | HTRA1 (0.49) | HTRA1RORCTACR1 | |
| SCHEMBL1827825 | 0.88 | HTRA1 (0.49) | HTRA1RORCTACR1 | |
| SCHEMBL24645319 | 0.88 | HTRA1 (0.49) | HTRA1RORCTACR1 | |
| SCHEMBL2379316 | 0.88 | HTRA1 (0.49) | HTRA1RORCTACR1 | |
| SCHEMBL29035325 | 0.88 | HTRA1 (0.49) | HTRA1RORCTACR1 | |
| SCHEMBL16972087 | 0.86 | HTRA1 (0.50) | HTRA1RORCHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |