Ethylene

Ethylene

SCHEMBL28529930

C=C.O=C(O)c1cc(C(=O)O)cc(-n2cncn2)c1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.40
NR4A1 P22736 1/20 0.40
RAB9A P51151 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NSD2 O96028 1/20 0.37
G6PD P11413 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
MAPT P10636 2/20 0.36
HSP90AA1 P07900 1/20 0.36
HTT P42858 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28265833 0.96 KDM4E (0.44) KDM4ESMN1; SMN2ALDH1A1POLBNR4A1
Ethylene Glycol SCHEMBL28526361 0.90 SMN1; SMN2 (0.40) KDM4ESMN1; SMN2ALDH1A1POLBNR4A1
SCHEMBL29761880 0.88 KDM4E (0.41) KDM4ESMN1; SMN2ALDH1A1POLBRAB9A
SCHEMBL21819396 0.85 POLB (0.43) KDM4ESMN1; SMN2ALDH1A1POLBRAB9A
SCHEMBL31133412 0.85 POLB (0.43) KDM4ESMN1; SMN2ALDH1A1POLBRAB9A
SCHEMBL28526357 0.84 POLB (0.43) KDM4ESMN1; SMN2ALDH1A1POLBRAB9A
SCHEMBL21819425 0.82 CYP1A2 (0.44) KDM4ESMN1; SMN2ALDH1A1POLBCYP1A2
SCHEMBL31133374 0.82 CYP1A2 (0.44) KDM4ESMN1; SMN2ALDH1A1POLBCYP1A2
SCHEMBL2358311 0.81 KDM4E (0.45) KDM4ESMN1; SMN2POLBCYP3A4KEAP1
SCHEMBL28526358 0.80 MAPT (0.40) KDM4ESMN1; SMN2ALDH1A1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112316921-A Polyester fiber film for wastewater treatment and preparation method thereof 邓颖菁 2021-02-05 CN claimed
CN-112176446-A Antibacterial polyester fiber and preparation method thereof 邓颖菁 2021-01-05 CN claimed