Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21503612 | 1.00 | BTK (0.44) | BTKKDM1AMAOBPIK3CDACACB | |
| SCHEMBL28529931 | 1.00 | BTK (0.44) | BTKKDM1AMAOBPIK3CDACACB | |
| SCHEMBL24975362 | 0.91 | BTK (0.41) | BTKKDM1AMAOBPIK3CDNFKB1 | |
| SCHEMBL29279741 | 0.91 | BTK (0.41) | BTKKDM1AMAOBPIK3CDNFKB1 | |
| SCHEMBL29874615 | 0.84 | PIK3CD (0.39) | BTKKDM1AMAOBPIK3CDNFKB1 | |
| SCHEMBL29874623 | 0.82 | PIK3CD (0.41) | BTKKDM1AMAOBPIK3CDNFKB1 | |
| SCHEMBL21492528 | 0.82 | EPHX2 (0.43) | EPHX2 | |
| SCHEMBL21492525 | 0.82 | EPHX2 (0.43) | EPHX2 | |
| SCHEMBL29874307 | 0.81 | BTK (0.39) | BTKKDM1AMAOBPIK3CDNFKB1 | |
| SCHEMBL29874542 | 0.81 | FFAR4 (0.39) | BTKKDM1AMAOBPIK3CDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |