SCHEMBL28529969

SCHEMBL28529969

CC(C(=O)O)(C(=O)O)c1ccco1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 4/20 0.46
POLB P06746 3/20 0.46
MEN1 O00255 3/20 0.46
KDM4E B2RXH2 2/20 0.46
TSHR P16473 1/20 0.46
MAPT P10636 1/20 0.44
PTPN1 P18031 2/20 0.41
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
PKM P14618 1/20 0.39
PTPN7 P35236 1/20 0.39
BLM P54132 1/20 0.39
ESR2 Q92731 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HCAR2 Q8TDS4 1/20 0.37
CYP2C19 P33261 3/20 0.36
RAB9A P51151 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27964089 0.83 MAPT (0.44) KMT2AALDH1A1POLBMEN1KDM4E
SCHEMBL9402238 0.83 MAPT (0.44) KMT2AALDH1A1POLBMEN1KDM4E
Hydrochloric Acid SCHEMBL9402285 0.82 MAPT (0.43) KMT2AALDH1A1POLBMEN1KDM4E
SCHEMBL5041397 0.82 MAPT (0.43) KMT2AALDH1A1POLBMEN1KDM4E
SCHEMBL637383 0.80 MAPT (0.42) KMT2AALDH1A1POLBMEN1KDM4E
SCHEMBL3513098 0.80 MAPT (0.42) KMT2AALDH1A1POLBMEN1KDM4E
Bicarbonate SCHEMBL28968865 0.79 MAPT (0.49) KMT2AALDH1A1POLBMEN1KDM4E
SCHEMBL2075002 0.77 PTPN1 (0.42) KMT2AALDH1A1POLBMEN1KDM4E
SCHEMBL8478567 0.77 PTPN1 (0.42) KMT2AALDH1A1POLBMEN1KDM4E
SCHEMBL27396838 0.77 PTPN1 (0.42) KMT2AALDH1A1POLBMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108033916-B Preparation of amino acid ester compound and application of amino acid ester compound in preventing and treating tobacco diseases 贵州理工学院 2021-02-26 CN disclosed