Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513205 | 0.97 | TYR (0.46) | TYRHTTTP53CYP3A4MEN1 | |
| SCHEMBL11036500 | 0.95 | TYR (0.45) | TYRHTTTP53CYP3A4MEN1 | |
| SCHEMBL11038944 | 0.91 | TYR (0.46) | TYRHTTTP53CYP3A4MEN1 | |
| SCHEMBL8372546 | 0.86 | TYR (0.42) | TYRHTTTP53CYP3A4MEN1 | |
| SCHEMBL7755498 | 0.85 | PDE5A (0.42) | TYRHTTTP53MAPTALOX15 | |
| SCHEMBL10900128 | 0.85 | TYR (0.43) | TYRHTTTP53CYP3A4MEN1 | |
| SCHEMBL11158917 | 0.81 | TYR (0.49) | TYRHTTTP53CYP3A4MEN1 | |
| SCHEMBL8861378 | 0.81 | TYR (0.45) | TYRHTTTP53CYP3A4MEN1 | |
| SCHEMBL11095669 | 0.80 | TYR (0.47) | TYRHTTTP53CYP3A4MEN1 | |
| SCHEMBL419569 | 0.80 | TYR (0.47) | TYRHTTTP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112263542-A | Desonide nanoemulsion gel composition and preparation method thereof | 澳美制药厂有限公司 | 2021-01-26 | — | — | CN | claimed |