Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28536531 | 0.90 | ITGA5 (0.45) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 | |
| SCHEMBL21821295 | 0.86 | ITGA5 (0.47) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 | |
| SCHEMBL19283643 | 0.84 | ITGA5 (0.43) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 | |
| SCHEMBL19283607 | 0.84 | ITGA5 (0.43) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 | |
| SCHEMBL19283613 | 0.84 | ITGB6 (0.55) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 | |
| SCHEMBL19284026 | 0.84 | ITGA5 (0.48) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 | |
| SCHEMBL19283573 | 0.83 | ITGA5 (0.44) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 | |
| SCHEMBL21821307 | 0.83 | SMN1; SMN2 (0.48) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 | |
| SCHEMBL20743128 | 0.83 | ITGA5 (0.45) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 | |
| SCHEMBL21821305 | 0.83 | SMN1; SMN2 (0.48) | ITGA5ITGB6ITGB8HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153667-B | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2021-04-02 | — | — | CN | disclosed |