Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27869459 | 0.89 | PDE7A (0.40) | ALDH1A1HTR2AHTR2CPDE7A | |
| SCHEMBL31582992 | 0.86 | CYP2A13 (0.36) | ALDH1A1HTR2AHTR2CGAALMNA | |
| SCHEMBL26394921 | 0.82 | HTR2A (0.36) | ALDH1A1HTR2AHTR2CGAA | |
| SCHEMBL6552316 | 0.82 | HTR2A (0.39) | HTR2AGAAKMT2AKDM1ALMNA | |
| SCHEMBL21616543 | 0.80 | HTR2A (0.35) | ALDH1A1HTR2AHTR2CGAAPDE7A | |
| SCHEMBL30991116 | 0.79 | PDE7A (0.33) | HTR2AHTR2CPDE7AKDM1A | |
| SCHEMBL31582983 | 0.78 | HTR2A (0.32) | ALDH1A1HTR2AHTR2CGAA | |
| SCHEMBL26027089 | 0.74 | HTR2A (0.32) | HTR2AGAAKMT2AKDM1ALMNA | |
| SCHEMBL16867367 | 0.74 | KDM1A (0.39) | HTR2AKDM1A | |
| SCHEMBL30874720 | 0.74 | PDE7A (0.39) | HTR2AHTR2CGAAPDE7AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106644-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ALPHA-V BETA-1 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| CN-112430234-B | Novel KRAS G12C protein inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-112430234-A | Novel KRAS G12C protein inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2021-03-02 | — | — | CN | disclosed |