Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001580 | 0.90 | EGFR (0.68) | EGFR | |
| Formic Acid SCHEMBL28531942 | 0.88 | EGFR (0.66) | EGFR | |
| SCHEMBL28540132 | 0.88 | EGFR (0.60) | EGFR | |
| SCHEMBL25001901 | 0.87 | EGFR (0.70) | EGFR | |
| SCHEMBL25001584 | 0.85 | EGFR (0.54) | EGFRBTK | |
| SCHEMBL25001395 | 0.85 | EGFR (0.67) | EGFR | |
| SCHEMBL23442667 | 0.83 | EGFR (0.79) | EGFR | |
| SCHEMBL28540075 | 0.83 | EGFR (0.48) | EGFR | |
| SCHEMBL25001609 | 0.83 | EGFR (0.72) | EGFR | |
| SCHEMBL28532752 | 0.83 | EGFR (0.61) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-A | Novel aminopyrimidine EGFR (epidermal growth factor receptor) inhibitor | 齐鲁制药有限公司 | 2021-03-23 | — | — | CN | disclosed |