Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559837 | 0.98 | TSHR (0.56) | TSHRALDH1A1S1PR2S1PR1S1PR3 | |
| SCHEMBL8430095 | 0.96 | TSHR (0.67) | TSHRALDH1A1S1PR2S1PR1S1PR3 | |
| SCHEMBL11764042 | 0.96 | TSHR (0.67) | TSHRALDH1A1S1PR2S1PR1S1PR3 | |
| SCHEMBL31035758 | 0.96 | TSHR (0.67) | TSHRALDH1A1S1PR2S1PR1S1PR3 | |
| SCHEMBL9979412 | 0.96 | TSHR (0.67) | TSHRALDH1A1S1PR2S1PR1S1PR3 | |
| SCHEMBL3670005 | 0.96 | TSHR (0.67) | TSHRALDH1A1S1PR2S1PR1S1PR3 | |
| SCHEMBL5596749 | 0.92 | TSHR (0.60) | TSHRALDH1A1S1PR2S1PR1S1PR3 | |
| SCHEMBL3666728 | 0.92 | TSHR (0.54) | TSHRALDH1A1S1PR2S1PR1S1PR3 | |
| SCHEMBL28719109 | 0.91 | TSHR (0.56) | TSHRALDH1A1S1PR2S1PR1S1PR3 | |
| SCHEMBL4228975 | 0.89 | TSHR (0.46) | TSHRALDH1A1S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390831-B | Triplecene ring metal palladium compound and application thereof | 国信宝威(北京)科技有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-112390831-A | Triplecene ring metal palladium compound and application | 国信宝威(北京)科技有限公司 | 2021-02-23 | — | — | CN | disclosed |