Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 0.48 |
| ▸ | TACR1 | P25103 | 8/20 | 0.44 |
| ▸ | RORC | P51449 | 4/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532289 | 1.00 | CETP (0.48) | CETPTACR1RORCP2RY14MAPT | |
| SCHEMBL29200058 | 0.91 | TACR1 (0.48) | CETPTACR1RORCP2RY14MAPT | |
| SCHEMBL21619693 | 0.91 | TACR1 (0.48) | CETPTACR1RORCP2RY14MAPT | |
| SCHEMBL28534495 | 0.91 | TACR1 (0.48) | CETPTACR1RORCP2RY14MAPT | |
| SCHEMBL28539663 | 0.89 | TACR1 (0.42) | CETPTACR1RORCP2RY14MAPT | |
| SCHEMBL28539977 | 0.88 | TACR1 (0.43) | CETPTACR1RORCP2RY14MAPT | |
| SCHEMBL28536977 | 0.88 | TACR1 (0.43) | CETPTACR1RORCP2RY14MAPT | |
| SCHEMBL20371559 | 0.85 | HTRA1 (0.50) | CETPTACR1RORC | |
| SCHEMBL14555313 | 0.85 | HTRA1 (0.50) | CETPTACR1RORC | |
| SCHEMBL28537130 | 0.83 | TACR1 (0.44) | CETPTACR1RORCP2RY14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |